Replaces multiple actives
HA + collagen peptide + PDRN + antioxidant in one simpler common base.
One active for everything your skin needs
One molecule. Four biological mechanisms.
AcquaSea® is a sulphated extracellular polysaccharide obtained from the marine microalga Porphyridium cruentum. Its unique molecular architecture acts simultaneously across different layers of the skin to deliver a complete biological response.
Advanced hydration • Collagen activation • PDRN-like regeneration • Active protection
Greater efficacy. Less complexity. AcquaSea® enables more efficient formulations with a highly competitive performance-to-cost ratio per dose.
Simplifies formulation
Fewer ingredients, less testing and shorter development time.
Reduces total cost
The combined cost of several equivalent actives can clearly exceed that of AcquaSea®.
Effective from 1%
High performance-to-cost ratio per dose from low use levels.
The origin
Extreme adaptation. Extraordinary bioactivity.
Porphyridium cruentum is a marine microalga that has evolved over millions of years to survive extreme environments: high radiation, salinity variations, dehydration and oxidative stress.
This unique adaptive capacity activates natural protection, repair and defence mechanisms, giving rise to extraordinary bioactives with exceptional benefits for the skin. AcquaSea® transforms this biological intelligence into precision marine biotechnology for cosmetics.
3.000 m2of production capacity
512production units
Biotechnological process
1
Pure strain · non-GMO
Porphyridium cruentum from a certified strain bank.
2
Photobioreactor
512 units, 3,000 m² and 24/7 control with CO₂ capture.
3
Harvesting
Extraction of the culture medium enriched in extracellular polysaccharides (EPS).
4
Solvent-free purification
Mechanical separation using physical concentration and purification technologies.
5
AcquaSea®
Purified and standardised hydrogel, ready to formulate.
Solvent-free
Reused water
CO₂ fixation
Zero waste
Our assurance
Proprietary technology
Standardised biotechnology platforms and specialised microalgae know-how.
Scientific evidence
Proprietary and independent in vivo and in vitro results, supported by internationally relevant literature.
Full traceability
Advanced analytical control and complete traceability from strain to final batch.
Sustainable production
Blue biotechnology, a 100% natural and vegan product, with sustainability-aligned processes.
The molecule
The biological advantage behind superior hydration.
Hyaluronic acid set the standard for hydration. But modern skin needs more than water retention. AcquaSea® transforms hydration into a complete biological response.
1
Superior molecular architecture
- Composed of six different monosaccharides.
- 3.5–7% natural sulphation.
- Broad molecular-weight spectrum: 140–6,000 kDa.
- Complex, branched and well-balanced structure.
2
Key differential sulphation
- Greater water-binding capacity.
- Resistant to hyaluronidase.
- Greater stability and long-lasting effect.
- Greater affinity for cellular receptors.
- Mimics endogenous GAGs.
- Modulates FGF and TGF-β growth factors.
3
Multifunctional biological activity
- Provides intensive hydration across multiple skin layers.
- Biostimulates the skin: fibroblasts, endogenous HA and collagen.
- Protects against oxidative stress, pollution and blue light.
- Soothes and strengthens the skin barrier.
- Improves firmness, elasticity and radiance.
Superior to hyaluronic acid
| Conventional hyaluronic acid | AcquaSea® · Marine sulphated polysaccharide |
|---|---|
| Degrades over time through hyaluronidase activity. | Resistant to hyaluronidase for longer-lasting efficacy. |
| Acts mainly on the surface. | Acts across different layers: stratum corneum, epidermis and dermis. |
| Hydrates only, without biostimulating the skin. | Biostimulates: +50% endogenous HA and +26% collagen I. |
| Does not activate collagen or regeneration. | Activates regeneration through ADORA2A, with a PDRN-like mechanism. |
| Primarily immediate, short-term effect. | Long-lasting, cumulative and more complete effect. |
Mechanism of action across the skin layers
Stratum corneum · the barrier
- Strengthens the skin barrier.
- Reduces transepidermal water loss (−31% TEWL).
- Protects against external aggressors and blue light.
Epidermis · tone and evenness
- Improves tone and radiance.
- Stimulates endogenous HA production.
- Balances and soothes the skin, reducing imperfections.
- −34% dark spots and −13% redness at D28.
Dermis · the production hub
- Directly activates fibroblasts.
- +50% endogenous hyaluronic acid.
- +26% type I procollagen and +18% type III collagen.
- +14.7% elasticity and +14% dermal density at D28.
Scientific evidence
The science behind every claim.
Scientifically validated mechanism of action. Visible results. Real efficiency. Independent and proprietary studies on Porphyridium cruentum confirm the biological pathways behind AcquaSea® performance.
+26,7%Hydration
−31%TEWL · barrier function
+14,7%Elasticity
+26%Collagen I
−39,7%ROS · antioxidant action
−24,3%IL-8 · anti-inflammatory action
+50%Stimulated endogenous HA
AcquaSea® studies · In vivo
| Parameter | Result |
|---|---|
| Hydration | +26,7% |
| Water loss (TEWL) | −31% |
| Elasticity | +14,7% |
| Sebum production | −29,2% |
| Microcirculation | +14,9% |
Proprietary study · In vitro
| Parameter | Result |
|---|---|
| IL-8 reduction | −24,3% |
| ROS reduction | −39,7% |
| Cell viability and proteasome | Improves cellular health |
| Stimulated endogenous HA | +50% |
| ADORA2A activation vs NECA | 82% |
Conclusion: consistent biological activity across multiple pathways: hydration, matrix stimulation, protection and regeneration.
Independent scientific evidence
| Area | Key data | Action |
|---|---|---|
| ADORA2A receptor | 82% vs NECA reference | Activates the cellular-regeneration pathway |
| Extracellular matrix (collagen) | Procollagen I +26% · Collagen III +18% | Stimulates collagen production |
| Endogenous HA | +50% | Increases natural hyaluronic-acid synthesis |
| IL-8 / anti-inflammatory action | IL-8 inhibition · activity comparable to hydrocortisone | Reduces inflammation and protects the skin |
| Longevity genes | ATG7 +22% · ATG8 +16% · LAMP2A +34% · EPHA2 +23% | Promotes cellular renewal and longevity |
Clinically observed benefits
- Deep, long-lasting hydration.
- Strengthened skin barrier and reduced water loss.
- Improved firmness, elasticity and density.
- Reduced sebum and imperfections.
- More even tone and improved radiance.
- Soothing action and improved overall skin quality.
Why do these results matter?
- They activate key biological pathways: HA synthesis, collagen production, inflammation control and cellular longevity.
- Multi-level action: hydration + structure + regeneration + protection, from the surface to the dermis.
- Supported by independent science: confirmed by proprietary and independent studies.
- Formulation efficiency: one active can replace multiple ingredients.
The formulation platform
An intelligent base for unlimited creation.
From active to formulation architecture: AcquaSea® is a common platform for developing specific solutions and complete ranges with maximum efficacy and technical consistency.
The AcquaSea® ecosystem
AcquaSeaShield
Ectoin · Ceramides
Barrier · Anti-pollution · SensitivityAcquaSeaLift
Copper Tripeptide‑1 · Argireline
Firmness · Anti-ageingAcquaSeaBright
Tranexamic acid · Oligo-68
Dark-spot correction · RadianceAcquaSeaBalance
Niacinamide · Azelaic acid
Sebum · Pores · Combination skinAcquaSeaCalm
Panthenol · Beta-glucan
Barrier · Soothing · Reactive skinYour custom formula
AcquaSea® + your differentiating active
Customised · Any claimAdvantages for your development
Modularity
Design complete ranges from the same functional base.
Technical consistency
The same active, science and formulation logic across the entire range.
Formulation efficiency
Fewer raw materials, less testing and lower development cost.
Architecture → tailored solutions
Sebum regulation · oily and combination skin · pores
Dark-spot correction · uneven tone · radiance
Anti-ageing · wrinkles · firmness · density
Sensitivity · reactive skin · barrier
Anti-pollution · environmental stress · blue light
Ideal for innovative formulations
- Compatible with cosmetic actives and ingredients.
- Stable across a broad pH and temperature range.
- Suitable for foams, emulsions, gels, serums, masks and sticks.
- Effective from 1%, with a high performance-to-cost ratio.
AcquaSea® simplifies formulation architecture and enables highly functional concepts with a very competitive balance of efficacy, versatility and formulation complexity.
Sustainable from the source
- 100% marine, vegan and non-GMO origin.
- Traceable production: 512 photobioreactors and 3,000 m² of installed capacity.
- Compatible with COSMOS / NATRUE-certifiable concepts.
- 100% natural and obtained without solvents.
- Aligned with sustainability and blue-economy claims.
Make AcquaSea® the functional core of your next cosmetic range.
Request a sample, technical documentation, formulation support or the development of a complete AcquaSea®-based family.